Searchable abstracts of presentations at key conferences in endocrinology

ea0015p311 | Steroids | SFEBES2008

Testosterone increases kidney weight in orchiectomized male Wistar rats but not dihydrotestosterone

Michaelis Marten , Hofmann Peter , Rohde Wolfgang , Goetze Franziska , Quinkler Marcus

Introduction: Androgens are known to play an important role in renal tubular epithelial cell growth, hypertrophy and erythropoetin production, however the exact mechanisms are not clear yet. 5α-dihydrotestosterone is synthesized primarily in gonads and skin, and is the most used androgen in studies. However, little is known about testosterone effects in non-gonadal tissues.Methods: Male Wistar rats aged 8–10 weeks were orchiectomized and put on...